A few things:
12GB of Triple-Channel RAM would be better than the 16 GB of Dual-Channel.
Also, is 875W enough to power both of those cards and the rest of your system? I would almost consider 1000-1200W.
Last, you're not going to see any benefits in performance by using 6Gbps 7200rpm drives. The only way to take advantage of the faster SATA-6Gb spec would be SSD. Ultimately, I would suggest a single 160-256GB SSD for primary OS drive, and multiple RAID 7200rpm drives for media/storage.
What monitor setup are you going to go with?
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