My guesses:
1) Bad u-joint(s)
2) Bad wheel bearing(s). Beacuse load makes a difference, I would suspect the rear.
But could also be a diff or trans issue. Either internal or, as mentioned above, a mount.
Doesn't really sound like an engine problem, but I'm just guessing at all this.
Good luck figuring it out and please let us know if you find out what's going on.
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