Yes you use any mini itx board you like the one I used has one m2 spot you can also use ssd drives up to 6 sata drives
You can also buy a adapter card and plug in bus’s of another m2 slot
There are a lot of different mini itc mother boards out there I just used one for a amd processor I had and memory
The big ticket item is the custom power supply is the most important
https://www.mini-box.com/M4-ATX?sc=8&category=981
This is what makes it all work
It has turn on and off by start and stop it tells the mother board to turn on and to shut down with out a hard stop will not drain your battery only run the power until the computer shuts down the the power is off
Plus you can set timers on the power supply to do a proper shut down all controlled from pc over USB
That is the most important thing
Plus has anti thump turn on for amps also remote turn on for amp
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